How does communication between neurons become dysregulated?

Immunofluorescence

We identify cell-type specific changes in neuronal activity by analyzing molecular markers of activity (e.g., c-FOS)  in combination with neuropeptide (e.g., PACAP) expression.  

Slice Physiology

We identify cell-type specific adaptations in neuronal activity by using genetically encoded calcium indicators in combination with  neuropeptides markers (e.g., PACAP).

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