How does communication between neurons become dysregulated?
Immunofluorescence
We identify cell-type specific changes in neuronal activity by analyzing molecular markers of activity (e.g., c-FOS) in combination with neuropeptide (e.g., PACAP) expression.
Slice Physiology
We identify cell-type specific adaptations in neuronal activity by using genetically encoded calcium indicators in combination with neuropeptides markers (e.g., PACAP).